Do it every turn, and the advantage adds up quickly
Cards, Speed Duel OTS Packs, Yu-Gi-Oh
The initial combo was to play Dark Depths on Turn 1, play Urborg, Tomb of Yawgmoth into Vampire Hexmage on Turn 2, and then simply use Vampire Hexmage to removal all of the counters off of your Dark Depths at the end of your opponent's turn, get a 20/20 Marit Lage, and kill your opponent on Turn 3, as long as they didn't have a Path to Exile
Mox Poison Yet another card that I would really only recommend for a Vintage or I suppose Commander Cube, Mox Poison is a funny and powerful fixed version of a Mox
The PSA 10 pop for Umbreon VMax is already over 2000 and climbing daily
or Gruul Charm deals 3 damage to each creature with flying